ARRY-380 (analog )
Cat. No.：YN340059
CAS No. ：937265-83-3
| 产品名称: | ARRY-380 (analog ) |
| CAS No.: | 937265-83-3 |
| Chemical Name: | 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine |
| Synonyms: | HER2-Inhibitor-1,ARRY-380 analog,ARRY380 |
| 分子量: | 569.63 |
| 分子式: | C₂₉H₂₇N₇O₄S |
| SMILES: | O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5)C(C)=C4)N=CN=C3C=C2)O1)(C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ARRY-380 analog 是EGFR (ErbB1)的抑制剂，详情参见专利 WO2015153959A2，化合物 249。ARRY-380 是一种高效、选择性、ATP 竞争性的口服 HER2 抑制剂。 |
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Lyssikatos, J.P., Hicks, J.M., Marmsater, F.P., et al.N4-phenyl-quinazoline-4-amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases,(2017)
