Lazertinib
Cat. No.：YN340066
CAS No. ：1903008-80-9
| 产品名称: | Lazertinib |
| CAS No.: | 1903008-80-9 |
| Chemical Name: | N-[5-[[4-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]-2-pyrimidinyl]amino]-4-methoxy-2-(4-morpholinyl)phenyl]-2-propenamide |
| Synonyms: | YH25448; GNS-1480 |
| 分子量: | 554.64 |
| 分子式: | C₃₀H₃₄N₈O₃ |
| SMILES: | C=CC(NC1=CC(NC2=NC=CC(N3N=C(C4=CC=CC=C4)C(CN(C)C)=C3)=N2)=C(OC)C=C1N5CCOCC5)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lazertinib (YH25448) 是一种有效，可逆，可口服，可透过血脑屏障的，突变体选择性的第三代EGFR酪氨酸激酶抑制剂，可用于非小细胞肺癌的研究。 |
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| Solvent & Solubility: |
Yun, J., Hong, M.H., Kim, S.-Y., et al.YH25448, an irreversible EGFR-TKI with potent intracranial activity in EGFR mutant non–small cell lung cancerClin. Cancer Res.25(8),2575-2587(2019)
