AST2818 mesylate
Cat. No.：YN340083
CAS No. ：2130958-55-1
| 产品名称: | AST2818 mesylate |
| CAS No.: | 2130958-55-1 |
| Chemical Name: | N-[2-[[2-(dimethylamino)ethyl]methylamino]-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-6-(2,2,2-trifluoroethoxy)-3-pyridinyl]-2-propenamide, monomethanesulfonate |
| Synonyms: | 甲磺酸艾氟替尼 |
| 分子量: | 664.70 |
| 分子式: | C₂₉H₃₅F₃N₈O₅S |
| SMILES: | C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OCC(F)(F)F)N=C1N(CCN(C)C)C)=O.CS(=O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AST2818 mesylate 是一种EGFR抑制剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Shi, Y., Zhang, S., Hu, X., et al.Safety, clinical activity, and pharmacokinetics of alflutinib (AST2818) in patients with advanced NSCLC with EGFR T790M mutationJ. Thorac. Oncol.15(6),1015-1026(2020)
