JND3229
Cat. No.：YN340088
CAS No. ：2260886-64-2
| 产品名称: | JND3229 |
| CAS No.: | 2260886-64-2 |
| Chemical Name: | |
| Synonyms: | JND3229;JND 3229;N-(trans-4-(3-(2-Chlorophenyl)-7-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)cyclohexyl)propionamide;N-[4-[3-(2-Chlorophenyl)-7-[3-methyl-4-(4-methylpiperazin-1-yl)anilino]-2-oxo-4 |
| 分子量: | 617.18 |
| 分子式: | C₃₃H₄₁ClN₈O₂ |
| SMILES: | CC1=CC(NC2=NC(N([C@@H]3CC[C@@H](NC(CC)=O)CC3)C(N(C4=C(Cl)C=CC=C4)C5)=O)=C5C=N2)=CC=C1N6CCN(C)CC6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | JND3229 是一种高效的 EGFRC797S的第四代可逆抑制剂， IC50值为 5.8 nM ，同时对于EGFRL858R/T790M和 EGFRWT的 IC50值分别为 30.5 和 6.8 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
