Erlotinib Hydrochloride
Cat. No.：YN340091
| 产品名称: | Erlotinib Hydrochloride |
| CAS No.: | 183319-69-9 |
| Chemical Name: | N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine, monohydrochloride |
| Synonyms: | 盐酸埃罗替尼; CP-358774 Hydrochloride; NSC 718781 Hydrochloride; OSI-774 Hydrochloride |
| 分子量: | 429.90 |
| 分子式: | C₂₂H₂₄ClN₃O₄ |
| SMILES: | COCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Erlotinib Hydrochloride (CP-358774 Hydrochloride) 抑制EGFR激酶的IC50为 2 nM。 |
| IC50和靶点: | [{name:"EGFR:2 nM (IC50)"}] |
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| Solvent & Solubility: |
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Moyer, J.D., Barbacci, E.G., Iwata, K.K., et al.Induction of apoptosis and cell cycle arrest by CP-358,774, an inhibitor of epidermal growth factor receptor tyrosine kinaseCancer Res.57(21),4838-4848(1997)
Herbst, R.S., and Bunn, P.A., Jr.Targeting the epidermal growth factor receptor in non-small cell lung cancerClin. Cancer Res.9(16),5813-5824(2003)
