BMS-599626 Hydrochloride
Cat. No.：YN340094
| 产品名称: | BMS-599626 Hydrochloride |
| CAS No.: | 873837-23-1 |
| Chemical Name: | |
| Synonyms: | AC480 Hydrochloride |
| 分子量: | 567.01 |
| 分子式: | C₂₇H₂₈ClFN₈O₃ |
| SMILES: | O=C(OC[C@H]1NCCOC1)NC2=CN(C3=C2C)N=CN=C3NC4=CC5=C(C=C4)N(CC6=CC(F)=CC=C6)N=C5.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BMS-599626 Hydrochloride (AC480 Hydrochloride) 是一种选择性的口服生物利用度HER1和HER2抑制剂，其IC50分别为 20和 30 nM。BMS-599626 Hydrochloride 对 HER4 的 IC50值为 190 nM，对 VEGFR2、c-Kit、Lck、MEK的抑制强度降低了 100 倍。BMS-599626 Hydrochloride 抑制肿瘤细胞增殖，并有可能增加肿瘤对放疗的反应。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
