RTC-5
Cat. No.:YN340099
CAS No. :1423077-49-9
产品名称: | RTC-5 |
CAS No.: | 1423077-49-9 |
Chemical Name: | TRC-382 |
Synonyms: | TRC-382 |
分子量: | 510.96 |
分子式: | C₂₄H₂₂ClF₃N₂O₃S |
SMILES: | O=S(C1=CC=C(OC(F)(F)F)C=C1)(NCCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | RTC-5 (TRC-382) 是一种具有抗癌效力的优化吩噻嗪。RTC-5 显示针对EGFR驱动的癌症的异种移植模型的功效,其效果归因于 PI3K-AKT 和 RAS-ERK 信号传导的负调节。 |
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Kastrinsky, D. B., et al.: Bioorg. Med. Chem., 23, 6528 (2015)