Mutated EGFR-IN-2
Cat. No.：YN340116
| 产品名称: | Mutated EGFR-IN-2 |
| CAS No.: | 2050906-97-1 |
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| 分子量: | 562.64 |
| 分子式: | C₂₉H₃₅FN₈O₃ |
| SMILES: | C=CC(NC1=CC(NC2=NC=CC(N3C4=CC=C(F)C=C4N(C(C)C)C3=O)=N2)=C(OC)C=C1N(CCN(C)C)C)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mutated EGFR-IN-2 (compound 91) 突变选择性的EGFR抑制剂，有效抑制单突变体 EGFR (T790M) 和双突变体 EGFR (包括 L858R/T790M (IC50=＜1nM) 和 ex19del/T790M)，并且可以抑制单一功能获得性突变 EGFR (包括 L858R 和 ex19del) 的活性。Mutated EGFR-IN-2 具有抗肿瘤活性。 |
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