EGFR-IN-7
Cat. No.：YN340117
CAS No. ：2267329-76-8
| 产品名称: | EGFR-IN-7 |
| CAS No.: | 2267329-76-8 |
| Chemical Name: | |
| Synonyms: | TQB3804 |
| 分子量: | 694.60 |
| 分子式: | C₃₂H₄₁BrN₉O₂P |
| SMILES: | CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | EGFR-IN-7 (compound 34) 是一种有效选择性的EGFR激酶抑制剂，对 EGFR (WT) 和 EGFR (mutant C797S/T790M/L858R) 的IC50值分别为 7.92 nM 和 0.218 nM，具有抗肿瘤活性，详细信息请参考专利 WO2019015655A1。 |
| IC50和靶点: | [{name:"EGFR (WT):7.92 nM (IC50)"},{name: "EGFR (C797S/T790M/L858R):0.218 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
