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AG 555

Cat. No.:YN340172

  • CAS No. :133550-34-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: AG 555
      CAS No.: 133550-34-2
      Chemical Name: (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide
      Synonyms:Tyrphostin B46
      分子量:322.36
      分子式:C₁₉H₁₈N₂O₃
      SMILES:O=C(NCCCC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: AG 555 (Tyrphostin AG 555) 是一种有效的抗逆转录病毒药物,是一种有效的选择性EGFR抑制剂,可阻断Cdk2活化。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Gazit, A., Osherov, N., Posner, I., et al.Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinasesJ. Med. Chem.34(6),1896-1907(1991)

      Ben-Bassat, H., Vardi, D.V., Gazit, A., et al.Tyrphostins suppress the growth of psoriatic keratinocytesExp. Dermatol.4(2),82-88(1995)

      Esther, A., Iftach, S., and Esther, P.Inhibition of Moloney murine leukemia virus replication by tyrphostins, tyrosine kinase inhibitorsFEBS Lett.341(1),99-103(1994)

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