Rociletinib hydrobromide
Cat. No.：YN340181
CAS No. ：1446700-26-0
| 产品名称: | Rociletinib hydrobromide |
| CAS No.: | 1446700-26-0 |
| Chemical Name: | |
| Synonyms: | CO-1686 hydrobromide; AVL-301 hydrobromide; CNX-419 hydrobromide |
| 分子量: | 636.46 |
| 分子式: | C₂₇H₂₉BrF₃N₇O₃ |
| SMILES: | C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1)=O.[H]Br |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rociletinib hydrobromide (CO-1686 hydrobromide) 是一种可口服的EGFR突变型抑制剂，对 EGFRL858R/T790M 和 EGFRWT 的Ki值分别为 21.5 nM 和 303.3 nM。 |
| IC50和靶点: | [{name:"EGFRL858R/T790M:21.5 nM (Ki)"},{name: "EGFRT790M:303.3 nM (Ki)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
