Lifirafenib
Cat. No.：YN340213
CAS No. ：1446090-79-4
| 产品名称: | Lifirafenib |
| CAS No.: | 1446090-79-4 |
| Chemical Name: | |
| Synonyms: | BGB-283 |
| 分子量: | 478.42 |
| 分子式: | C₂₅H₁₇F₃N₄O₃ |
| SMILES: | O=C1NC2=NC=CC(OC3=CC=C(O[C@@]4([H])[C@]5([H])[C@@H]4C6=NC7=CC=C(C(F)(F)F)C=C7N6)C5=C3)=C2CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lifirafenib (BGB-283) 是新型高效的Raf激酶和EGFR抑制剂，对重组BRafV600E和EGFR的IC50值分别为23 和29 nM。 |
| IC50和靶点: | [{name:"EGFR:29 nM (IC50)"},{name: "BRafV600E:23 nM (IC50)"},{name: "EGFRL858R/T790M:495 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
