Osimertinib dimesylate
Cat. No.：YN340248
CAS No. ：2070014-82-1
| 产品名称: | Osimertinib dimesylate |
| CAS No.: | 2070014-82-1 |
| Chemical Name: | |
| Synonyms: | 奥希替尼二甲磺酸盐; AZD-9291 dimesylate; Mereletinib dimesylate |
| 分子量: | 691.82 |
| 分子式: | C₃₀H₄₁N₇O₈S₂ |
| SMILES: | CS(=O)(O)=O.C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C)C)C)=O.CS(=O)(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Osimertinib dimesylate (AZD-9291 dimesylate) 是不可逆的突变体选择性EGFR抑制剂；对EGFRL858R和EGFRL858R/T790M的IC50值分别为12 和 1 nM。 |
| IC50和靶点: | [{name:"EGFRL858R:12 nM (IC50)"},{name: "EGFRL858R/T790M:1 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
