β-Hydroxyisovalerylshikonin
Cat. No.:YN340280
产品名称: | β-Hydroxyisovalerylshikonin |
CAS No.: | 7415-78-3 |
Chemical Name: | |
Synonyms: | β-羟基异戊酰基紫草素 |
分子量: | 388.41 |
分子式: | C₂₁H₂₄O₇ |
SMILES: | CC(C)(O)CC(O[C@@H](C(C1=O)=CC(C2=C1C(O)=CC=C2O)=O)C/C=C(C)\C)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Beta-hydroxyisovalerylshikonin 是一种从Lithospermium radix中分离出的天然产物,是一种有效的PTK抑制剂, 对 EGFR 和 v-Src 受体作用的IC50分别为 0.7 μM 和 1 μM。Beta-hydroxyisovalerylshikonin 对多种肿瘤细胞系均有抑制作用,能高效诱导 NCI-H522 和 DMS114 细胞的死亡。 |
IC50和靶点: | |
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