Nazartinib mesylate
Cat. No.:YN340306
产品名称: | Nazartinib mesylate |
CAS No.: | 1508250-72-3 |
Chemical Name: | |
Synonyms: | EGF816 mesylate |
分子量: | 591.12 |
分子式: | C27H35ClN6O5S |
SMILES: | O=C(C1=CC(C)=NC=C1)NC2=NC3=CC=CC(Cl)=C3N2[C@H]4CN(C(/C=C/CN(C)C)=O)CCCC4.CS(=O)(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Nazartinib mesylate (EGF816 mesylate) 是一种新颖的EGFR抑制剂,对 EGFR(L858R/790M) 突变体的Ki和Kinact值分别为 31 nM 和 0.222 min−1。 |
IC50和靶点: | [{name:"EGFRL858R/T790M:31 nM (Ki)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |