EGFR-IN-1
Cat. No.:YN340308
产品名称: | EGFR-IN-1 |
CAS No.: | 1625677-63-5 |
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分子量: | 514.58 |
分子式: | C28H30N6O4 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | EGFR-IN-1 (compound 24) 是一种具有口服活性的,不可逆的突变体选择性L858R/T790MEGFR抑制剂。与野生型EGFR相比,EGFR-IN-1 对 Gefitinib 耐药的EGFRL858R/T790M 有 100 倍的抑制作用。EGFR-IN-1 对 H1975 细胞和 HCC827 细胞具有较强的抗增殖活性。具有抗肿瘤活性。 |
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