EGFR/ErbB-2/ErbB-4 inhibitor-2
Cat. No.：YN340309
| 产品名称: | EGFR/ErbB-2/ErbB-4 inhibitor-2 |
| CAS No.: | 179248-61-4 |
| Chemical Name: | 6,7-dimethoxy-N-[4-(phenylmethoxy)phenyl]-4-quinazolinamine |
| Synonyms: | |
| 分子量: | 387.4 |
| 分子式: | C23H21N3O3 |
| SMILES: | COC1=C(OC)C=C(C(NC2=CC=C(OCC3=CC=CC=C3)C=C2)=NC=N4)C4=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | EGFR/ErbB-2/ErbB-4 inhibitor-2 (Compound 5) 是一种EGFR和ErbB抑制剂，IC50分别为 0.017 μM，0.08 μM，1.91 μM。 |
| IC50和靶点: | [{name:"EGFR:0.017 μM (IC50)"},{name: "ErbB2:0.08 μM (IC50)"},{name: "ErbB4:1.91 μM (IC50)"}] |
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| Solvent & Solubility: |
Cockerill, S., Stubberfield, C., Stables, J., et al.Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2Bioorg. Med. Chem. Lett.11(11),1401-1405(2001)
Anastassiadis, T., Deacon, S.W., Devarajan, K., et al.Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivityNat. Biotechnol.29(11),1039-1045(2011)
