Mutated EGFR-IN-3
Cat. No.：YN340317
| 产品名称: | Mutated EGFR-IN-3 |
| CAS No.: | 2375107-27-8 |
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| 分子量: | 508.59 |
| 分子式: | C31H29FN4O2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mutated EGFR-IN-3，化合物 3，是EGFR(L858R/T790M)和EGFR(L858R/T790M/C797S)突变体的有效，具有 ATP 竞争性和高选择性的变构二苯并二氮杂酮抑制剂，抑制 EGFR(L858R/T790M) 和 EGFR(L858R/T790M/C797S) 的IC50值分别为 12 nM 和 13 nM。 |
| IC50和靶点: | [{name:"EGFRL858R/T790M:12 nM (IC50)"},{name: "EGFRC797S:13 nM (IC50)"}] |
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