Gefitinib-d
Cat. No.：YN340321
| 产品名称: | Gefitinib-d |
| CAS No.: | 269390-69-4 |
| Chemical Name: | N-(4-chlorophenyl)-2-[(4-pyridinylmethyl)amino]-benzamide |
| Synonyms: | |
| 分子量: | 337.8 |
| 分子式: | C19H16ClN3O |
| SMILES: | ClC1=CC=C(NC(C2=CC=CC=C2NCC3=CC=NC=C3)=O)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | VEGFR-IN-1 (compound 3) 是一种有效的血管生成抑制剂，对于KDR、Flt-1、c-Kit、EGF-R 和 c-Src，IC50分别为 0.02、0.18、0.24、7.3 和 7 µM。 |
| IC50和靶点: | [{name:"KDR:0.02 μM (IC50)"},{name: "Flt-1:0.18 μM (IC50)"},{name: "EGFR:0.24 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Furet, P., Bold, G., Hofmann, F., et al.Identification of a new chemical class of potent angiogenesis inhibitors based on conformational considerations and database searchingBioorg. Med. Chem. Lett.13(18),2967-2971(2003)
