Inetetamab
Cat. No.:YN340325
CAS No. :5334-30-5
产品名称: | Inetetamab |
CAS No.: | 5334-30-5 |
Chemical Name: | 1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Synonyms: | PP 3 |
分子量: | 211.2 |
分子式: | C11H9N5 |
SMILES: | NC1=C2C=NN(C3=CC=CC=C3)C2=NC=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PP 3 (Compound 3) 是一种EGFR酪氨酸激酶抑制剂,IC50为 2.7 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Ungefroren, H., Sebens, S., Groth, S., et al.The Src family kinase inhibitors PP2 and PP1 block TGFβ-mediated cellular responses by direct and differential inhibition of type I and type II TGFβreceptorsCurr. Cancer Drug Targets11(4),524-535(2011)
Tatton, L., Morley, G.M., Chopra, R., et al.The Src-selective kinase inhibitor PP1 also inhibits kit and Bcr-Abl tyrosine kinasesJ. Biol. Chem.278(7),4847-4853(2003)