Allitinib
Cat. No.：YN340333
| 产品名称: | Allitinib |
| CAS No.: | 897383-62-9 |
| Chemical Name: | |
| Synonyms: | AST-1306; ALS 1306 |
| 分子量: | 448.877 |
| 分子式: | C24H18ClFN4O2 |
| SMILES: | C(NC1C=CC2C(C=1)=C(NC1=CC=C(OCC3=CC=CC(F)=C3)C(Cl)=C1)N=CN=2)(=O)C=C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Allitinib (AST-1306) 是一种具有口服活性且不可逆的EGFR和ErbB2抑制剂，IC50分别为 0.5 和 3 nM。Allitinib 抑制ErbB4，IC50为 0.8 nM。Allitinib 是一种苯胺基喹唑啉化合物，具有抗癌活性。 |
| IC50和靶点: | [{name:"EGFR:0.5 nM (IC50)"},{name: "ErbB2:3 nM (IC50)"},{name: "EGFRL858R/T790M:12 nM (IC50)"},{name: "ErbB4:0.8 nM (IC50)"}] |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
