Uzansertib
Cat. No.：YN340340
| 产品名称: | Uzansertib |
| CAS No.: | 1620012-39-6 |
| Chemical Name: | |
| Synonyms: | INCB053914 |
| 分子量: | 513.521 |
| 分子式: | C26H26F3N5O3 |
| SMILES: | C(C(NC1=CN=C2[C@@H](O)CCC2=C1N1C[C@@H](C)[C@H](O)[C@@H](N)C1)=O)1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Uzansertib (INCB053914) 是一种具有口服活性的，ATP 竞争性泛-PIM激酶抑制剂，对于PIM1，PIM2 和PIM3的IC50分别为 0.24 nM，30 nM 和 0.12 nM。Uzansertib 对多种血液肿瘤细胞系具有广泛的抗增殖活性。 |
| IC50和靶点: | [{name:"PIM1:0.24 nM (IC50)"},{name: "PIM2:30 nM (IC50)"},{name: "PIM3:0.12 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
