limertinib
Cat. No.：YN340342
CAS No. ：1934259-00-3
| 产品名称: | limertinib |
| CAS No.: | 1934259-00-3 |
| Chemical Name: | |
| Synonyms: | ASK120067 |
| 分子量: | 546.072 |
| 分子式: | C29H32ClN7O2 |
| SMILES: | 暂无 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | limertinib (ASK120067) 是一种有效的口服活性EGFRT790M抑制剂 (IC50:0.3 nM)，对EGFRWT(IC50:6.0 nM) 具有选择性。limertinib 是用于非小细胞肺癌 (NSCLC) 研究的第三代 EGFR-TKI。 |
| IC50和靶点: | [{name:"EGFRT790M:0.5 nM (IC50)"},{name: "EGFRL858R/T790M:0.3 nM (IC50)"},{name: "EGFR (WT):6 nM (IC50)"},{name: "EGFRExon 19 deletion:0.5 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
