1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
Cat. No.：YN340347
| 产品名称: | 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea |
| CAS No.: | 1313019-65-6 |
| Chemical Name: | |
| Synonyms: | 1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea, STAT3-IN-7 |
| 分子量: | 431.8 |
| 分子式: | C21H13ClF3N3O2 |
| SMILES: | FC(F)(F)C1=CC(=CC=C1Cl)NC(=O)NC2=CC=C(OC3=CC=C(C=C3)C#N)C=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | STAT3-IN-7 是一种 Sorafenib 的衍生物，可有效抑制STAT3的磷酸化。STAT3-IN-7 通过依赖 SHP-1 的STAT3失活诱导细胞凋亡 (apoptosis)，不抑制激酶活性，并具有抗癌作用。 |
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