EGFR-IN-1 hydrochloride
Cat. No.:YN340349
产品名称: | EGFR-IN-1 hydrochloride |
CAS No.: | 2227455-78-7 |
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分子量: | 551.04 |
分子式: | C28H31ClN6O4 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | EGFR-IN-1 hydrochloride 是一种口服活性不可逆的突变型选择性L858R/T790MEGFR抑制剂。与野生型EGFR相比,EGFR-IN-1 hydrochloride 对 Gefitinib 耐药的EGFRL858R/T790M 有 100 倍的抑制作用。EGFR-IN-1 hydrochloride 对 H1975 细胞和 HCC827 细胞具有较强的抗增殖活性。具有抗肿瘤活性。 |
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