SU14813
Cat. No.：YN440100
CAS No. ：627908-92-3
规格
价格(RMB)
库存
| 产品名称: | SU14813 |
| CAS No.: | 627908-92-3 |
| Chemical Name: | 5-[(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide |
| Synonyms: | SU 014813 |
| 分子量: | 442.48 |
| 分子式: | C₂₃H₂₇FN₄O₄ |
| SMILES: | O=C(C1=C(C)NC(C=C2C(NC3=C2C=C(F)C=C3)=O)=C1C)NC[C@H](O)CN4CCOCC4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SU14813是多靶点受体酪氨酸激酶抑制剂，抑制VEGFR2，VEGFR1，PDGFRβandKIT的IC50值分别为50，2，4，15 nM。 |
| IC50和靶点: | [{name:"VEGFR1:2 nM (IC50)"},{name: "VEGFR2:50 nM (IC50)"},{name: "PDGFRβ:4 nM (IC50)"},{name: "KIT:15 nM (IC50)"}] |
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| Solvent & Solubility: |
Patnya, S., Laird, A.D., Mendel, D.B., et al.SU14813: a novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activityMol. Cancer Ther.5(7),1774-1782(2006)
