BMS-794833
Cat. No.：YN440099
CAS No. ：1174046-72-0
规格
价格(RMB)
库存
| 产品名称: | BMS-794833 |
| CAS No.: | 1174046-72-0 |
| Chemical Name: | N-[4-[(2-amino-3-chloro-4-pyridinyl)oxy]-3-fluorophenyl]-5-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-pyridinecarboxamide |
| Synonyms: | |
| 分子量: | 468.84 |
| 分子式: | C₂₃H₁₅ClF₂N₄O₃ |
| SMILES: | ClC1=C(OC2=CC=C(NC(C3=CNC=C(C4=CC=C(F)C=C4)C3=O)=O)C=C2F)C=CN=C1N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BMS-794833 是VEGFR2和Met的抑制剂，来自专利WO2009094417， 化合物实例1，IC50值分别为15 和 1.7 nM。 |
| IC50和靶点: | [{name:"VEGFR2:15 nM (IC50)"},{name: "Met:1.7 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Borzilleri, R.M., and Cai, Z.-W.4-Pyridinone compounds and their use for cancer,(2009)
Moran-Jones, K.The therapeutic potential of targeting the HGF/cMET axis in ovarian cancerMol. Diagn. Ther.20(3),199-212(2016)
