TAS-115
Cat. No.:YN440208
产品名称: | TAS-115 |
CAS No.: | 1190836-34-0 |
Chemical Name: | |
Synonyms: | TAS-115,H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide |
分子量: | 518.56 |
分子式: | C₂₇H₂₃FN₄O₄S |
SMILES: | O=C(C1=C(OC)C=C2N=CC=C(OC3=CC=C(NC(NC(CC4=CC=CC=C4)=O)=S)C=C3F)C2=C1)NC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | TAS-115 是一种有效的VEGFR和c-Met/HGFR抑制剂,能够抑制 rVEGFR2 和 rMET 的活性,IC50值分别为 30 和 32 nM。 |
IC50和靶点: | [{name:"VEGFR2:30 nM (IC50)"},{name: "c-Met:32 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |