Merestinib dihydrochloride
Cat. No.：YN440332
CAS No. ：1206801-37-7
规格
价格(RMB)
库存
| 产品名称: | Merestinib dihydrochloride |
| CAS No.: | 1206801-37-7 |
| Chemical Name: | |
| Synonyms: | LY2801653 dihydrochloride |
| 分子量: | 625.45 |
| 分子式: | C₃₀H₂₄Cl₂F₂N₆O₃ |
| SMILES: | [H]Cl.[H]Cl.O=C(C1=CC=C(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC5=C(N(C)N=C5)C=C4C6=CNN=C6)C(F)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Merestinib dihydrochloride (LY2801653 dihydrochloride) 是一种有效的口服生物可利用的具有抗肿瘤活性的c-Met抑制剂 (Ki=2 nM)。Merestinib dihydrochloride 对 MST1R (IC50=11 nM)、FLT3 (IC50=7 nM)、AXL (IC50=2 nM)、MERTK (IC50=10 nM)、TEK (IC50=63 nM)、ROS1、DDR1/2 (IC50=0.1/7 nM) 和 MKNK1/2 (IC5 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
