Toxoflavin
Cat. No.:YN450011
产品名称: | Toxoflavin |
CAS No.: | 84-82-2 |
Chemical Name: | 1,6-dimethyl-pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-dione |
Synonyms: | Xanthothricin; |
分子量: | 193.16 |
分子式: | C₇H₇N₅O₂ |
SMILES: | O=C(C1=NC=NN(C)C1=N2)N(C)C2=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Toxoflavin (Xanthothricin) 是一种TCF4/β-catenin复合物抑制剂,也是一种KDM4A抑制剂,具有抗肿瘤活性 。 |
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Lepourcelet, M., Chen, Y.N., France, D.S., et al.Small-molecule antagonists of the oncogenic Tcf/β-catenin protein complexCancer Cell5(1),91-102(2004)
Wei, W., Chua, M.-S., Grepper, S., et al.Small molecule antagonists of the Tcf4/β-catenin complex inhibit the growth of HCC cells in vitro and in vivoInt. J. Cancer126(10),2426-2436(2010)