ICG-001
Cat. No.：YN450091
CAS No. ：780757-88-2
规格
价格(RMB)
库存
| 产品名称: | ICG-001 |
| CAS No.: | 780757-88-2 |
| Chemical Name: | (6S,9aS)-hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide |
| Synonyms: | (6S,9aS)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxooctahydro-1H-pyrazino[1,2-a]pyrimidine-1-carboxamide;(6S,9AS)-N-BENZYL-6-(4-HYDROXYBENZYL)-8-(NAPHTHALEN-1-YLMETHYL)-4,7-DIOXOOCTAHYDRO-1H-PYRAZINO[1,2-A]PYRIMIDINE-1-CARBO...;2H-PYR |
| 分子量: | 548.63 |
| 分子式: | C₃₃H₃₂N₄O₄ |
| SMILES: | O=C(NCC1=CC=CC=C1)N2CCC(N([C@@]2(CN(C3=O)CC4=C5C=CC=CC5=CC=C4)[H])[C@H]3CC6=CC=C(C=C6)O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ICG-001 是β-catenin/TCF介导的转录抑制剂。 ICG-001 特异性结合 CREB 蛋白起作用，IC50为3 μM。ICG-001 选择性地阻断 β-catenin/CBP 相互作用而不干扰 β-catenin/p300 相互作用。 |
| IC50和靶点: | |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
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