Isocurcumenol
Cat. No.：YN483100
| 产品名称: | Isocurcumenol |
| CAS No.: | 24063-71-6 |
| Chemical Name: | octahydro-3S-methyl-8aS-methylene-5-(1-methylethylidene)-6H-3aS,6-epoxyazulen-6R-ol |
| Synonyms: | |
| 分子量: | 234.33 |
| 分子式: | C₁₅H₂₂O₂ |
| SMILES: | O[C@@]1(C2)/C(C[C@]3(O1)[C@@H](C)CC[C@@]3([H])C2=C)=C(C)/C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Isocurcumenol 可从Curcuma zedoariaRhizomes 中分离得到，是ERα的抑制剂。具有抗肿瘤活性。其对 DLA 和 KB 癌细胞的IC50分别为 99.1 µg/mL 和 178.2 µg/mL。 |
| IC50和靶点: | |
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Chen, C., Long, L., Zhang, F., et al.Antifungal activity, main active components and mechanism of Curcuma longa extract against Fusarium graminearumPLoS One13(3),e0194284(2018)
Lakshmi, S., Padmaja, G., and Remani, P.Antitumour effects of isocurcumenol isolated from Curcuma zedoaria rhizomes on human and murine cancer cellsInt. J. Med. Chem.,253962(2011)
Matsuda, H., Ninomiya, K., Morikawa, T., et al.Inhibitory effect and action mechanism of sesquiterpenes from zedoariae rhizoma on D-galactosamine/lipopolysaccharide-induced liver injuryBioorg. Med. Chem. Lett.8(4),339-344(1998)
