Zearalanone
Cat. No.：YN483345
| 产品名称: | Zearalanone |
| CAS No.: | 5975-78-0 |
| Chemical Name: | (3S)-3,4,5,6,9,10,11,12-octahydro-14,16-dihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione |
| Synonyms: | 玉米赤霉酮 |
| 分子量: | 320.38 |
| 分子式: | C₁₈H₂₄O₅ |
| SMILES: | O=C(O[C@@H](C)CCC1)C2=C(O)C=C(O)C=C2CCCCCC1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Zearalenone 是由镰刀菌属Fusarium产生的，在几种谷物中生长的非甾体雌激素霉菌毒素。 Zearalenone 具有较低的急性毒性和致癌性。Zearalenone 对雌激素受体有激动作用，在几种动物中表现出明显的雌激素和合成代谢特性，对动物的生殖系统会产生严重影响。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Baldwin, R.S., Williams, R.D., and Terry, M.K.Zeranol: A review of the metabolism, toxicology, and analytical methods for detection of tissue residuesRegul. Toxicol. Pharmacol.3(1),9-25(1983)
Migdalof, B.H., Dugger, H.A., Heider, J.G., et al.Biotransformation of zeranol: Disposition and metabolism in the female rat, rabbit, dog, monkey and manXenobiotica13(4),209-221(1983)
Le Guevel, R., and Pakdel, F.Assessment of oestrogenic potency of chemicals used as growth promoter by in-vitro methodsHum. Reprod.16(5),1030-1036(2001)
Molina-Molina, J.M., Real, M., Jimenez-Diaz, I., et al.Assessment of estrogenic and anti-androgenic activities of the mycotoxin zearalenone and its metabolites using in vitro receptor-specific bioassaysFood Chem. Toxicol.74,233-239(2016)
Aoyama, K., Ishikuro, E., Noriduki, H., et al.Formation ratios of zearalanone, zearalenols, and zearalanols versus zearalenone during incubation of Fusarium semitectum on sorghum and ratios in naturally contaminated sorghumFood Hyg. Saf. Sci.56(6),247-251(2015)
