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(R)-Equol

Cat. No.:YN480386

  • CAS No. :221054-79-1

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    • 生物活性
    • 参考文献
    • 产品名称: (R)-Equol
      CAS No.: 221054-79-1
      Chemical Name: 3,4-dihydro-3R-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
      Synonyms:(+)-Equol
      分子量:242.27
      分子式:C₁₅H₁₄O₃
      SMILES:OC1=CC=C2C[C@H](C3=CC=C(O)C=C3)COC2=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (R)-Equol 是ERα和ERβ的激动剂,Ki值分别为 27.4 和 15.4 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Setchell, K.D.R., Clerici, C., Lephart, E.D., et al.S-equol, a potent ligand for estrogen receptor β, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial floraAm. J. Clin. Nutr.81(5),1072-1079(2005)

      Muthyala, R.S., Ju, Y.H., Sheng, S., et al.Equol, a natural estrogenic metabolite from soy isoflavones: Convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and betaBioorg. Med. Chem.12(6),1559-1567(2004)

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