WAY-200070
Cat. No.:YN480110
产品名称: | WAY-200070 |
CAS No.: | 440122-66-7 |
Chemical Name: | 7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol |
Synonyms: | WAY 200070 |
分子量: | 306.11 |
分子式: | C₁₃H₈BrNO₃ |
SMILES: | OC1=CC(Br)=C(OC(C2=CC=C(O)C=C2)=N3)C3=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | WAY-200070是选择性的雌激素受体激动剂,IC50值为2.3 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Malamas, M.S., Manas, E.S., McDevitt, R.E., et al.Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligandsJ. Med. Chem.47(21),5021-5040(2004)
Hughes, Z.A., Liu, F., Platt, B.J., et al.WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agentNeuropharmacology54(7),1136-1142(2008)
F., C., Chen, S., Liu, S., et al.Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice testNeuropharmacology95,226-233(2015)
Alonso-Magdalena, P., Ropero, A.B., García-Arévalo, M., et al.Antidiabetic actions of an estrogen receptor β selective agonistDiabetes62(6),2015-2025(2013)