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WAY-200070

Cat. No.:YN480110

  • CAS No. :440122-66-7

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    • 产品名称: WAY-200070
      CAS No.: 440122-66-7
      Chemical Name: 7-bromo-2-(4-hydroxyphenyl)-5-benzoxazolol
      Synonyms:WAY 200070
      分子量:306.11
      分子式:C₁₃H₈BrNO₃
      SMILES:OC1=CC(Br)=C(OC(C2=CC=C(O)C=C2)=N3)C3=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: WAY-200070是选择性的雌激素受体激动剂,IC50值为2.3 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Malamas, M.S., Manas, E.S., McDevitt, R.E., et al.Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-β ligandsJ. Med. Chem.47(21),5021-5040(2004)

      Hughes, Z.A., Liu, F., Platt, B.J., et al.WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agentNeuropharmacology54(7),1136-1142(2008)

      F., C., Chen, S., Liu, S., et al.Effects of lorazepam and WAY-200070 in larval zebrafish light/dark choice testNeuropharmacology95,226-233(2015)

      Alonso-Magdalena, P., Ropero, A.B., García-Arévalo, M., et al.Antidiabetic actions of an estrogen receptor β selective agonistDiabetes62(6),2015-2025(2013)

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