PHTPP
Cat. No.：YN480247
CAS No. ：805239-56-9
规格
价格(RMB)
库存
| 产品名称: | PHTPP |
| CAS No.: | 805239-56-9 |
| Chemical Name: | 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-phenol |
| Synonyms: | |
| 分子量: | 423.31 |
| 分子式: | C₂₀H₁₁F₆N₃O |
| SMILES: | OC1=CC=C(C2=C3N=C(C(F)(F)F)C=C(C(F)(F)F)N3N=C2C4=CC=CC=C4)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | PHTPP 是一种选择性雌激素受体 β (ERβ) 拮抗剂，其选择性是 ERα 的 36 倍。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Compton, D.R., Sheng, S., Carlson, K.E., et al.Pyrazolo[1,5-a]pyrimidines: Estrogen receptor ligands possessing estrogen receptor β antagonist activityJ. Med. Chem.47(24),5872-5893(2004)
Chan, K.K.L., Leung, T.H.Y., Chan, D.W., et al.Targeting estrogen receptor subtypes (ERα and ERβ) with selective ER modulators in ovarian cancerJ. Endocrinol.221(2),325-336(2014)
