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Enclomiphene citrate

Cat. No.:YN480695

  • CAS No. :7599-79-3

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    • 产品名称: Enclomiphene citrate
      CAS No.: 7599-79-3
      Chemical Name: 2-[4-[(1E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethyl-ethanamine, 2-hydroxy-1,2,3-propanetricarboxylate
      Synonyms:恩氯米芬柠檬酸盐; (E)-Clomiphene citrate; trans-Clomiphene citrate; Enclomifene citrate
      分子量:598.08
      分子式:C₃₂H₃₆ClNO₈
      SMILES:Cl/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(CC)CC)C=C2)\C3=CC=CC=C3.O=C(CC(C(O)=O)(O)CC(O)=O)O.[(E)]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Enclomiphene citrate 是一种有效、可口服的oestrogen receptor拮抗剂,具有抗雌激素作用。
      IC50和靶点:
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      In Vivo:
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    • Hill, S., Arutchelvam, V., and Quinton, R.Enclomiphene, an estrogen receptor antagonist for the treatment of testosterone deficiency in menIDrugs12(2),109-119(2009)

      Wyss, R.H., Karsznia, R., Heinrichs, W.L., et al.Inhibition of uterine receptor binding of estradiol by anti-estrogens (clomiphene and CL-868)J. Clin. Endocrinol. Metab.28(12),1824-1828(1968)

      Huang, S.-R., and Miller, W.L.Estrogenic and antiestrogenic effects of enclomiphene and zuclomiphene on gonadotropin secretion by ovine pituitary cells in cultureEndocrinology112(2),442-448(1983)

      Weissenberg, R., Dar, Y., and Lunenfeld, B.The effect of clomiphene citrate and its Zu or En isomers on the reproductive system of the immature male ratAndrologia24(3),161-165(1992)

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