DPN
Cat. No.:YN480805
产品名称: | DPN |
CAS No.: | 1428-67-7 |
Chemical Name: | 4-hydroxy-α-(4-hydroxyphenyl)-benzenepropanenitrile |
Synonyms: | Diarylpropionitrile |
分子量: | 239.27 |
分子式: | C₁₅H₁₃NO₂ |
SMILES: | OC1=CC=C(CC(C#N)C2=CC=C(O)C=C2)C=C1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | DPN (Diarylpropionitrile) 是一种非甾体雌激素受体ERβ选择性配体,其EC50值为 0.85 nM。DPN 在许多神经系统疾病具有神经保护作用。 |
IC50和靶点: | [{name:"ERβ:0.85 nM (EC50)"}] |
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Meyers, M.J., Sun, J., Carlson, K.E., et al.Estrogen receptors-β potency-selective ligands: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogusJ. Med. Chem.44,4230-4251(2001)