BHPI
Cat. No.:YN480911
产品名称: | BHPI |
CAS No.: | 56632-39-4 |
Chemical Name: | 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one |
Synonyms: | |
分子量: | 331.36 |
分子式: | C₂₁H₁₇NO₃ |
SMILES: | O=C1NC2=C(C=CC=C2C)C1(C3=CC=C(O)C=C3)C4=CC=C(O)C=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | BHPI是核内受体ER_alpha_抑制剂,可抑制癌细胞蛋白合成和活化未折叠蛋白反应(UPR)。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Andruska, N.D., Zheng, X., Yang, X., et al.Estrogen receptor α inhibitor activates the unfolded protein response, blocks protein synthesis, and induces tumor regressionProc. Natl. Acad. Sci. USA112(15),4737-4742(2015)