SAR439859
Cat. No.：YN481084
CAS No. ：2114339-57-8
规格
价格(RMB)
库存
| 产品名称: | SAR439859 |
| CAS No.: | 2114339-57-8 |
| Chemical Name: | |
| Synonyms: | SAR439859 |
| 分子量: | 554.48 |
| 分子式: | C₃₁H₃₀Cl₂FNO₃ |
| SMILES: | O=C(C1=CC=C(C(C2=CC=C(O[C@@H]3CN(CCCF)CC3)C=C2)=C(C4=CC=C(Cl)C=C4Cl)CCC5)C5=C1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SAR439859 (compound 43d) 是一种具有口服活性，非甾体和选择性雌激素受体降解剂 (SERD)。SAR439859 是一种有效的 ER 拮抗剂，具有 ER 降解活性，EC50为 0.2 nM。SAR439859 可在 ER+乳腺癌中表现出强大的抗肿瘤功效和有限的交叉耐药性。 |
| IC50和靶点: | [{name:"ERα:0.2 nM (EC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
