Erteberel
Cat. No.：YN481620
CAS No. ：533884-09-2
规格
价格(RMB)
库存
| 产品名称: | Erteberel |
| CAS No.: | 533884-09-2 |
| Chemical Name: | (3aS,4R,9bR)-1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-cyclopenta[c][1]benzopyran-8-ol |
| Synonyms: | LY500307 |
| 分子量: | 282.33 |
| 分子式: | C₁₈H₁₈O₃ |
| SMILES: | OC1=CC=C2C([C@@](CCC3)([H])[C@@]3([H])[C@H](C4=CC=C(O)C=C4)O2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Erteberel (LY500307) 是有效，选择性的雌激素受体 β (ERβ) 激动剂，Ki和EC50分别为1.54 nM，3.61 nM。抗肿瘤活性。 |
| IC50和靶点: | [{name:"ERβ:1.54 nM (Ki)"},{name: "ERβ:3.61 nM (EC50)"}] |
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| Solvent & Solubility: |
Sareddy, G.R., Li, X., Liu, J., et al.Selective estrogen receptor β agonist LY500307 as a novel therapeutic agent for glioblastomaSci. Rep.6:24185,(2016)
Norman, B.H., Dodge, J.A., Richardson, T.I., et al.Benzopyrans are selective estrogen receptor β agonists with novel activity in models of benign prostatic hyperplasiaJ. Med. Chem.49(21),6155-6157(2006)
