Lasofoxifene Tartrate
Cat. No.：YN481747
CAS No. ：190791-29-8
规格
价格(RMB)
库存
| 产品名称: | Lasofoxifene Tartrate |
| CAS No.: | 190791-29-8 |
| Chemical Name: | (5R,6S)-5,6,7,8-tetrahydro-6-phenyl-5-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2-naphthalenol, (2S,3S)-2,3-dihydroxybutanedioate |
| Synonyms: | CP-336156 |
| 分子量: | 563.64 |
| 分子式: | C₃₂H₃₇NO₈ |
| SMILES: | OC1=CC=C2[C@@H](C3=CC=C(OCCN4CCCC4)C=C3)[C@@H](C5=CC=CC=C5)CCC2=C1.O=C(O)[C@@H](O)[C@H](O)C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lasofoxifene酒石酸盐是一种非甾体类的选择性雌激素受体调节剂 (SERM)。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Ke, H.Z., Paralkar, V.M., Grasser, W.A., et al.Effects of CP-336,156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus, and body composition in rat modelsEndocrinology139(4),2068-2076(1998)
Cummings, S.R., Ensrud, K., Delmas, P.D., et al.Lasofoxifene in postmenopausal women with osteoporosisN. Engl. J. Med.362(8),686-696(2010)
Gennari, L., Merlotti, D., and Nuti, R.Selective estrogen receptor modulator (SERM) for the treatment of osteoporosis in postmenopausal women: Focus on lasofoxifeneClin. Interv. Aging5,19-29(2010)
Kumar, P., and Song, Z.H.CB2 cannabinoid receptor is a novel target for third-generation selective estrogen receptor modulators bazedoxifene and lasofoxifeneBiochem. Bioph. Res. Commun.443(1),144-149(2014)
