Toremifene citrate
Cat. No.:YN481769
产品名称: | Toremifene citrate |
CAS No.: | 89778-27-8 |
Chemical Name: | 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine, 2-hydroxy-1,2,3-monopropanetricarboxylate |
Synonyms: | 枸橼酸托瑞米芬; Z |
分子量: | 598.08 |
分子式: | C₃₂H₃₆ClNO₈ |
SMILES: | ClCC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3.O=C(CC(C(O)=O)(O)CC(O)=O)O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Toremifene citrate (Z-Toremifene citrate) 是第二代选择性雌激素受体调节剂,对雌激素受体的IC50为 1μM。Toremifene citrate 还可以有效抑制传染性EBOV Zaire和Marburg (MARV),IC50分别为 0.07 µM 和 2.6 µM。 |
IC50和靶点: | |
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Goldstein, S.R., Siddhanti, S., Ciaccia, A.V., et al.A pharmacological review of selective oestrogen receptor modulatorsHum. Reprod. Update6(3),212-224(2000)