Ospemifene
Cat. No.:YN481853
产品名称: | Ospemifene |
CAS No.: | 128607-22-7 |
Chemical Name: | 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-ethanol |
Synonyms: | 奥培米芬; FC-1271a |
分子量: | 378.89 |
分子式: | C₂₄H₂₃ClO₂ |
SMILES: | ClCC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCO)C=C2)\C3=CC=CC=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ospemifene 是一种非雌激素选择性雌激素受体 (estrogen receptor) 调节剂 (SERM),对雌激素受体α (ERα)和ERβ的Kis 值分别为 380 和 410 nM。Ospemifene 可用于阴道萎缩乳腺癌的研究。 |
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Unkila, M., Kari, S., Yatkin, E., et al.Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopauseJ. Steroid Biochem. Mol. Biol.138,107-115(2013)