Anastrozole
Cat. No.：YN481386
CAS No. ：120511-73-1
规格
价格(RMB)
库存
| 产品名称: | Anastrozole |
| CAS No.: | 120511-73-1 |
| Chemical Name: | α1,α1,α3,α3-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile |
| Synonyms: | 阿那曲唑; ZD1033 |
| 分子量: | 293.37 |
| 分子式: | C₁₇H₁₉N₅ |
| SMILES: | CC(C)(C#N)C1=CC(C(C)(C#N)C)=CC(CN2C=NC=N2)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Anastrozole 是一种选择性的芳香酶 (aromatase) 抑制剂，抑制胎盘芳香化酶，IC50为 15 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Grimm, S.W., and Dyroff, M.C.Inhibition of human drug metabolizing cytochromes P450 by anastrozole, a potent and selective inhibitor of aromataseDrug Metab. Dispos.25(5),598-602(1997)
Plourde, P.V., Dyroff, M.C., and Dukes, M.Arimidex®: A potent and selective fourth-generation aromatase inhibitorBreast Cancer Res. Treat.30(1),103-111(1994)
Kubatka, P., Sadlonová, V., Kajo, K., et al.Chemopreventive effects of anastrozole in a premenopausal breast cancer modelAnticancer Res.28(5A),2819-2823(2008)
