MRT67307
Cat. No.：YN410038
CAS No. ：1190378-57-4
| 产品名称: | MRT67307 |
| CAS No.: | 1190378-57-4 |
| Chemical Name: | |
| Synonyms: | MRT67307 HCl |
| 分子量: | 464.60 |
| 分子式: | C₂₆H₃₆N₆O₂ |
| SMILES: | O=C(NCCCNC1=NC(NC2=CC=CC(CN3CCOCC3)=C2)=NC=C1C4CC4)C5CCC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MRT67307 是IKKε和TBK-1的双抑制剂，IC50分别为 160 和 19 nM。MRT67307 也可抑制ULK1和ULK2，IC50分别为 45 和 38 nM。MRT67307 还抑制细胞自噬 (autophagy)。 |
| IC50和靶点: | [{name:"TBK1:19 nM (IC50, at 0.1 mM ATP)"},{name: "IKKε:160 nM (IC50, at 0.1 mM ATP)"},{name: "ULK2:38 nM (IC50)"},{name: "ULK1:45 nM (IC50)'}, 'Autophagy'] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
