IKK 16
Cat. No.：YN410054
CAS No. ：873225-46-8
| 产品名称: | IKK 16 |
| CAS No.: | 873225-46-8 |
| Chemical Name: | IKK-16 |
| Synonyms: | IKK Inhibitor VII,IKK16,IKK-16 |
| 分子量: | 483.63 |
| 分子式: | C₂₈H₂₉N₅OS |
| SMILES: | O=C(C1=CC=C(NC2=NC=CC(C3=CC4=CC=CC=C4S3)=N2)C=C1)N5CCC(N6CCCC6)CC5 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | IKK 16 是一种选择性的 IκB 激酶 (IKK) 抑制剂，作用于IKK2，IKK complex和IKK1，IC50分别为 40 nM，70 nM 和 200 nM。IKK 16 还抑制富亮氨酸重复激酶 2 (LRRK 2)，IC50为 50 nM。 |
| IC50和靶点: | [{name:"IKK2:40 nM (IC50)"},{name: "IKK1:200 nM (IC50)"},{name: "IKK:70 nM (IC50)"},{name: "LRRK2:50 nM (IC50)"}] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Xie, H.Z., et al.: J. Biomole. Stru. Dyn., 29, 165 (2011)
Waelchli, R., et al.: Bioorg. Med. Chem. Lett., 16, 108 (2006)
Nagarajan, S., et al.: Bioorg. Med. Chem., 18, 3951 (2010)
