LY2409881 trihydrochloride
Cat. No.：YN410085
CAS No. ：946518-60-1
| 产品名称: | LY2409881 trihydrochloride |
| CAS No.: | 946518-60-1 |
| Chemical Name: | 2-[5-chloro-2-[[3-(4-methyl-1-piperazinyl)propyl]amino]-4-pyrimidinyl]-N-cyclopropyl-benzo[b]thiophene-4-carboxamide, trihydrochloride |
| Synonyms: | LY2409881 |
| 分子量: | 594.43 |
| 分子式: | C₂₄H₃₂Cl₄N₆OS |
| SMILES: | O=C(C1=C(C=C(C2=NC(NCCCN3CCN(C)CC3)=NC=C2Cl)S4)C4=CC=C1)NC5CC5.[H]Cl.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LY2409881 trihydrochloride 是一种选择性的 IκB 激酶 β (IKK2) 抑制剂，IC50为 30 nM。 |
| IC50和靶点: | [{name:"IKK2:30 nM (IC50)"}] |
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| Solvent & Solubility: |
Deng, C., Lipstein, M., Rodriguez, R., et al.The novel IKK2 inhibitor LY2409881 potently synergizes with histone deacetylase inhibitors in preclinical models of lymphoma through the downregulation of NF-κBClin. Cancer. Res21(1),134-145(2015)
