Sappanone A
Cat. No.：YN410157
| 产品名称: | Sappanone A |
| CAS No.: | 102067-84-5 |
| Chemical Name: | 3-[(3,4-dihydroxyphenyl)methylene]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one |
| Synonyms: | |
| 分子量: | 284.3 |
| 分子式: | C16H12O5 |
| SMILES: | OC1=CC=C(C(/C(CO2)=C/C3=CC=C(O)C(O)=C3)=O)C2=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sappanone A 是一种高异黄烷酮，通过调节Nrf2和NF-κB表现出抗炎作用。Sappanone A 可以减轻卵清蛋白引起的哮喘中的过敏性气道炎症。 |
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Lin, L.-G., Xie, H., Li, H.-L., et al.Naturally occurring homoisoflavonoids function as potent protein tyrosine kinase inhibitors by c-Src-based high-throughput screeningJ. Med. Chem.51(15),4419-4429(2008)
Jeong, H.J., Kim, Y.M., Kim, J.H., et al.Homoisoflavonoids from Caesalpinia sappan displaying viral neuraminidases inhibitionBiol. Pharm. Bull.35(5),786-790(2012)
Das, B.C., Thirupathi, P., Ravikanth, B., et al.Isolation, synthesis, and bioactivity of homoisoflavonoids from Caesalpinia pulcherrimaChem. Pharm. Bull. (Tokyo)57(10),1139-1141(2009)
Lee, S., Choi, S.-Y., Choo, Y.-Y., et al.Sappanone A exhibits anti-inflammatory effects via modulation of Nrf2 and NF-κBInt. Immunopharmacol.28(1),328-336(2015)
Liu, X., Yu, D., and Wang, T.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthmaInt. Arch. Allergy. Immunol.170(3),180-186(2016)
