LTβR-IN-1
Cat. No.：YN410167
CAS No. ：2189366-77-4
| 产品名称: | LTβR-IN-1 |
| CAS No.: | 2189366-77-4 |
| Chemical Name: | |
| Synonyms: | |
| 分子量: | 320.352 |
| 分子式: | C18H16N4O2 |
| SMILES: | C(NC1=NC2=CC=CC=C2N1)(=O)[C@@H](N1CC2=C(C1=O)C=CC=C2)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LTβR-IN-1 是一种有效的、选择性淋巴毒素 β 受体 (LTβR) 抑制剂。LTβR-IN-1 选择性抑制依赖于 TNF12A 的 p52 的核易位，不影响 TNF-α 受体介导的 p65 的核易位。LTβR-IN-1 抑制受 TWEAK 或 Anti-LTβR 刺激的 p52 核易位，IC50分别为 17 μM。LTβR-IN-1 以配体非依赖性方式调节 NF-kB 信号通路。 |
| IC50和靶点: | |
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